After dominating the boxing world, Adonis Creed has been thriving in both his career and family life. When a childhood friend and former boxing prodigy, Damien Anderson, resurfaces after serving a long sentence in prison, he is eager to prove that he deserves his shot in the ring. The face-off between former friends is more than just a fight. To settle the score, Adonis must put his future on the line to battle Damien - a fighter who has nothing to lose.

The former World Heavyweight Champion Rocky Balboa serves as a trainer and mentor to Adonis Johnson, the son of his late friend and former rival Apollo Creed.