The Duttons face a new set of challenges in the early 20th century, including the rise of Western expansion, Prohibition and the Great Depression.

A married couple are thrown into a crisis when the wife, an under-appreciated and stressed "supermom," suffers a post-traumatic breakdown during the holiday season, causing her to regress to her college-age, party-girl self.

Follow a new generation of the Dutton family during the early twentieth century when pandemics, historic drought, the end of Prohibition and the Great Depression all plague the mountain west, and the Duttons who call it home.