Stand-up comic Mae Martin navigates a passionate, messy new relationship with her girlfriend, George, while dealing with the challenges of sobriety.

Married couple Bob and Susan Howard decide to see a marriage counselor named Judy Small, who appears trustworthy but harbors dark and conflicted impulses

Physicists Leonard and Sheldon find their nerd-centric social circle with pals Howard and Raj expanding when aspiring actress Penny moves in next door.

Uptight and straight-laced, FBI Special Agent Sarah Ashburn is a methodical investigator with a reputation for excellence--and hyper-arrogance. Shannon Mullins, one of Boston P.D.'s "finest," is foul-mouthed and has a very short fuse, and uses her gut instinct and street smarts to catch the most elusive criminals. Neither has ever had a partner, or a friend for that matter. When these two wildly incompatible law officers join forces to bring down a ruthless drug lord, they become the last thing anyone expected: Buddies.