In the year 2045, cybernetic mercenary Motoko Kusanagi returns to Section 9 to face a dangerous new threat: the posthumans.

Years after the horrors of Raccoon City, Leon and Claire find themselves consumed by a dark conspiracy when a viral attack ravages the White House.

Resurrected as an Arisen, Ethan sets out to vanquish the Dragon that took his heart. But with every demon he battles, his humanity slips further away.