Rizwan Khan, a Muslim from the Borivali section of Mumbai, has Asperger's syndrome. He marries a Hindu single mother, Mandira, in San Francisco. After 9/11, Rizwan is detained by authorities at LAX who treat him as a terrorist because of his condition and his race.

Three men accidentally stumble into the world of crime when they start kidnapping for small ransoms in order to improve their lifestyles. However, they soon realise that it is not a bad business.

When Vikram gets tapped to play the male lead in a Bollywood film, he can't believe his luck. But it may ruin his relationship with his girlfriend.